The Four Pathogenic Factors Involved in AcneAn increase in the levels of androgens before and during adolescence leads to the production of greater amounts of sebum.The bacterium Propionibacterium acnes, which is resident on the skin of even healthy individuals, thrives on sebum. Increased sebum production in acne patients results in a proliferation of this micro-organism.Something goes awry in the infundibulum of the follicle in acne patients that causes cells from the follicle wall to clump together. This abnormal keratinization results in the clogged pores, or microcomedones, that can later proceed to other acne lesions.The presence of P acnes triggers the release of chemotactic factors that cause inflammation, as manifested by papules, pustules, and nodules.
It is a well known fact that men and women have different kinds of skin, and they are often plagued by different kinds of skin problems. However, there are also common skin problems that both sexes encounter, and one of these is acne. Skin care for acne prone men may be slightly different from the women's in a few distinct ways. While women are more prone to acne due the make-up and lotions they put on their faces or skin, men are prone to acne because of the activities that they indulge in, and also certain factors in their environments.
Even though Acne Differin Cream only contains a small amount of the active ingredient, it can cause severe irritation to those with sensitive skin. Only a small amount is needed for each application, and irritation can occur if more than the necessary amount is applied. Differin Cream also can increase the risk of developing severe sunburn, so natural and artificial sun should be avoiding while using this prescription. A stinging sensation can occur directly after applying Acne Differin Cream, and irritation can occur if Differin Cream is applied to the eyes, mouth, or any areas with mucous membranes.
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